It is exhausting to consider opioid deaths are dropping while you’re strolling on Vancouver’s Downtown Eastside, the place B.C.’s drug disaster is most seen.
Open drug use continues to be frequent and on a dry day, you may rely on seeing dozens of individuals unconscious on the sidewalk.
However the numbers do not lie: overdose deaths in 2024 decreased 12 per cent in B.C. and throughout the nation compared to the previous 12 months, based on January information from the province and March information from Health Canada.
The epidemic has killed 50,928 Canadians since 2016 — that is all of the seats in Rogers Stadium in Toronto, after which some. In response to Well being Canada, 21 individuals a day, on common, die from poisonous medicine on this nation.
However the declines mark a small however distinct shift within the nation’s overdose epidemic, which was formally declared a well being emergency in B.C. 9 years in the past final month.
The downward pattern is much more pronounced within the U.S., the place drops in fatalities of as much as 45 per cent have been seen in states like North Carolina, based on the Facilities for Illness Management and Prevention (CDC), which aggregates state numbers.
Nevertheless, any progress might be undermined if both nation sees a dramatic shift in drug provide or hurt discount measures, warns Nabarun Dasgupta, a senior scientist on the College of North Carolina’s Opioid Information Lab, which has been closely monitoring the shift within the U.S.
“The worst factor we may do proper now could be crack down too rapidly on fentanyl,” he mentioned.
However that is what Canada’s federal authorities has vowed to do in border measures initally crafted to stave off tariff threats from the U.S. — despite the fact that Canada has questioned the rationale, provided that lower than one kilogram of fentanyl has been seized on the U.S.-Canada border since January.
Stopping “manufacturing and trafficking of unlawful fentanyl” is a part of the scope of the $1.3-billion Canada Border Plan, which additionally guarantees to strengthen border security.
Staving off tariffs
Inside our borders, the federal government can be making plans to more strictly control some of the secondary chemicals used within the unlawful manufacturing of fentanyl, on prime of the already managed important elements.
In a press release to CBC Information, the RCMP’s nationwide workplace says it is already uncovered “many chemical compounds” which are used as reducing brokers for artificial opioids like fentanyl, together with veterinary medicine — not fit to be eaten.
China had additionally made strikes to display a co-operation on fentanyl to keep away from tariffs, releasing a White Paper in March to point out the actions it is taken to “curb the unlawful manufacturing, smuggling, and trafficking of fentanyl-related substances,” together with reining in precursor chemical compounds.
Those that work in hurt discount and individuals who use medicine worry a repeat of what occurred in the course of the pandemic, when closed borders and disrupted provide chains turned a consider “elevated toxicity,” a key challenge mentioned in a Canada-U.S. joint white paper.
The report, co-authored by U.S. and Canadian authorities, together with Well being Canada and the Public Well being Company of Canada, famous in March 2022 that “adjustments within the availability of gear might contribute to drug shortages, elevated toxicity, stockpiling, and adjustments in tolerance amongst individuals who use medicine, which can improve substance-related harms.”
“It is occurred dozens of occasions earlier than with medicine,” mentioned Dasgupta on the Opioid Information Lab.
“A brand new stronger opioid will come into the market. The market is totally primed for that form of a shift.”

What’s subsequent?
The illicit drug provide is at all times evolving.
From month to month, sure unregulated medicine like fentanyl or methamphetamine will seem in various quantities in samples examined by drug checkers at a neighborhood degree, or by autopsies and toxicology checks.
The unpredictability of elements is what makes accessing this uncontrolled provide so harmful, says Sarah Blyth, government director of the Overdose Prevention Society (OPS).
“If it will get exhausting to get fentanyl, there will likely be different medicine that flood the market,” she mentioned. “What is the subsequent drug? Is it carfentanil? Then we’re worse off.”
Carfentanil, like fentanyl, is an artificial opioid. Folks fear about it leaching into the drug provide, as a result of it is about 100 occasions extra poisonous than fentanyl. It appears to be like like desk salt and just some grains will be deadly.
Frequent adjustments within the unlawful drug provide are after all felt deepest by the individuals who eat them.
It is vital to recollect drug customers are all any person’s brother, sister, daughter or son, says Nick Reagan, a 31-year-old from Calgary who has used opioids for 10 years to handle his power ache after a automotive accident.
He lives in Vancouver’s Downtown Eastside and worries about his drug provide being reduce off by crackdowns or turning into extra contaminated.
“My life is in danger,” he advised CBC Information.
It isn’t exhausting to think about overdose deaths numbers getting worse in B.C., given it was just some years in the past that just about seven people a day were dying, in comparison with nearly 5 a day as of January 2025. On the time, then-chief coroner Lisa Lapointe pointed to the risks of individuals utilizing poisonous medicine alone, in addition to provide chains disrupted by the COVID-19 pandemic making a void for drug makers to supply extra highly effective substances.
CBC Information requested Well being Canada about its new Precursor Threat Administration Unit, which helps lead the crackdown, on whether or not coverage makers had thought-about how an abrupt scarcity of fentanyl may have an effect on drug customers.
In a press release, the company mentioned the unit was following precedent set by related federal authorities initiatives up to now, including that “substance use harms and the overdose disaster are pushed by advanced and interrelated elements, and require a spread of providers and helps to handle them.”
The impacts of the extra enforcement may not be instantly apparent. It takes time to gather information on an unregulated drug provide, and if the availability does begin to change, it will take no less than few weeks for a sample to emerge, says Dasgupta.
3 theories
Dasgupta’s staff in North Carolina continues to be attempting to nail down the explanations behind the numerous lower in overdose deaths, which have been seen in all U.S. states besides Nevada and Alaska.
He has three primary theories, which at first appeared like whole anomalies.
The primary is an obvious shift towards a extra diversified drug provide that is much less based mostly on fentanyl and consists of plenty of elements, like different artificial opioids or amphetamines. Merely put, the drug provide might be getting saturated with substances which are much less harmful than massive quantities of fentanyl.
“Individuals are telling us in our area research that the dope is not the identical because it was once,” Dasgupta mentioned.
Then there’s the drug customers themselves. Individuals who often crunch the numbers on overdose deaths know there is a sure cohort of those who generally makes up a majority of fatalities. In Canada in 2024, 73 per cent of overdoses deaths occurred to males aged 30 to 39, according to Health Canada.
Within the U.S., about 70 per cent of overdose deaths hit males of their late-40s to mid-50s. Dasgupta suspects components of that cohort might have stopped utilizing medicine or might be dying of different causes.

‘It provides up’
The final speculation for the decline is extra hopeful.
Interventions might be having an actual influence. Remedy choices, together with lifesaving opioid reversal medicine like naxolone, which individuals often carry with them, or applications to cut back the stigma of drug use or educate younger individuals on the risks, is perhaps making a dent.
It provides up, says Sarah Blyth, who says the Overdose Prevention Society saves individuals day-after-day in numerous methods.
Nonetheless, she stays sceptical of a everlasting enchancment within the long-running drug disaster, as she personally is aware of individuals who have just lately died from the availability. Optimism on this rolling disaster is well damaged and individuals are determined to see issues enhance.
“Nobody desires to see anymore individuals dying,” Blyth mentioned. “I wish to see individuals residing the most effective life that they will.”
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